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Home ->Articles -> Adalimumab (Humira®) and Biosimilars | ||
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Adalimumab (Humira®) and Biosimilars Adalimumab is a biologic drug product that is launched by Abbvie and is approved for medical use in the United States in 2002. This drug is originally sold under the brand name Humira®. Adalimumab is a fully human monoclonal antibody that functions by blocking soluble and transmembrane TNF-α (tumor necrosis factor-alpha) which causes inflammation in the body. This drug has been used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. So far, a few adalimumab (Humira®) biosimilars have been approved in the market including Amjevita (adalimumab-atto), Cyltezo (adalimumab-adbm), Hyrimoz (adalimumab-adaz), Hadlima (adalimumab-bwwd), Abrilada (adalimumab-afzb), Hulio (adalimumab-fkjp), Yusimry (adalimumab-aqvh), Idacio (adalimumab-aacf) and Yuflyma (adalimumab-aaty). Adalimumab is produced by recombinant DNA technology using a mammalian cell expression system. RGBiotech offers adlimumab expressing plasmid vectors to assist your biosimilar development. Product Name: pBD-hFerL(H)-Adalimumab(Neo) Plasmid Vector Item No.: PPBD-3-1 Plasmid Vector Map: Quality Control: Figure 1. pBD-hFerL(H)-Adalimumab(Neo) Plasmid Vector Map Figure 2. Enzyme digestion of pBD-hFerL(H)-Adalimumab(Neo) plasmid vector. |
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