INTRODUCTION

Becaplermin (brand name Regranex) is a recombinant human platelet-derived growth factor (PDGF) that is used in the treatment of lower extremity diabetic neuropathic ulcers.

This plasmid is designed for expressing Becaplermin in yeast (Saccharomyces cerevisiae) expression system.

PRODUCT INFORMATION

Item No.: PPBD-31
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Becaplermin
Brand Names: Regranex
Classification: Protein based therapies
Amino Acid Sequence: Identical to DB00102

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Yang CL, Chen JT, Deng F, Tang HZ, Tan XY, Luo SQ. [Construction and identification of yeast expression vectors containing human platelet-derived growth factor B-chain gene]. Di Yi Jun Yi Da Xue Xue Bao. 2004 Mar;24(3):273-6. Chinese.

[2] Nagai MK, Embil JM. Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers. Expert Opin Biol Ther. 2002 Feb;2(2):211-8. doi: 10.1517/14712598.2.2.211. PMID: 11849120.

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