INTRODUCTION

Botulinum toxin type A (brand names Botox, Botox Cosmetic, Daxxify, Dysport, Jeuveau, Xeomin), also known as onabotulinumtoxinA, is a neurotoxin that is used in the treatment of chronic sialorrhea, muscle spasticity, dystonia, as well as in cosmetic applications.

This plasmid is designed for expressing Botulinum toxin type A in E.coli expression system.

PRODUCT INFORMATION

Item No.: PPBD-37
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Botulinum toxin type A
Brand Names: Botox, Botox Cosmetic, Daxxify, Dysport, Jeuveau, Xeomin
Classification: Protein based therapies
Amino Acid Sequence: Identical to DB00083

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

Vertiev IuV, Zdanovskiĭ AG, Borinskaia SA, Martin T, Gening EL, Iankovskiĭ NK. Effektivnaia ékspressiia v kletkakah E. coli fragmentov gena botulinicheskogo neĭrotoksina tipa A, kodiruiushchikh L-tsep' i H-tsep', s obrazovaniem produktov, vyzyvaiushchikh protektivnyĭ immunitet k vvedeniiu toksina [Effective expression of fragments of a botulinum neurotoxin type A gene, coding for the L-chain and H-chain in E. coli, with formation of products causing protective immunity to administration of the toxin]. Mol Gen Mikrobiol Virusol. 2000;(4):3-7. Russian.

Contact Us