INTRODUCTION

Cerliponase alfa (brand names Brineura) is a recombinant enzyme Coagulation Factor XIII A-Subunit that is used to treat people with congenital deficiency or mutation of Factor XIII.

This plasmid is designed for expressing Catridecacog in yeast (Saccharomyces cerevisiae) expression system.

PRODUCT INFORMATION

Item No.: PPBD-43
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options for promoter and selection marker, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Cerliponase alfa
Brand Names: Brineura
Classification: Recombinant Enzyme
Action type: Replacement therapy
Amino Acid Sequence: Identical to DB13173

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

Guhaniyogi J, Sohar I, Das K, Stock AM, Lobel P. Crystal structure and autoactivation pathway of the precursor form of human tripeptidyl-peptidase 1, the enzyme deficient in late infantile ceroid lipofuscinosis. J Biol Chem. 2009 Feb 6;284(6):3985-97.

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