INTRODUCTION

Digoxin Immune Fab (Ovine) (brand names Digifab, Digibind) is a sheep antibody that is used as an antidote to digoxin overdose (severe digitalis toxicity).

This plasmid is designed for expressing Digoxin Immune Fab (Ovine) in mammalian expression system.

PRODUCT INFORMATION

Item No.: PPBD-58
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options for promoter and selection marker, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Digoxin Immune Fab (Ovine)
Brand Name(s): Digifab, Digibind
Classification: Monoclonal antibody (mAb)
Amino Acid Sequence: Identical to DB00076

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

DiDomenico RJ, Walton SM, Sanoski CA, Bauman JL. Analysis of the use of digoxin immune fab for the treatment of non-life-threatening digoxin toxicity. J Cardiovasc Pharmacol Ther. 2000 Apr;5(2):77-85.

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