INTRODUCTION

Dostarlimab (brand name Jemperli) is a humanized monoclonal antibody that targets and blocks programmed cell death 1 (PDCD1). Dostarlimab is used in the treatment of mismatch repair deficient endometrial cancers.

This plasmid is designed for expressing Dostarlimab in mammalian expression system.

PRODUCT INFORMATION

Item No.: PPBD-60
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options for promoter and selection marker, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Dostarlimab
Brand Name(s): Jemperli
Classification: Monoclonal antibody (mAb)
Target: programmed cell death 1 (PDCD1), PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1
Amino Acid Sequence: Identical to DB15627

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

Green AK, Feinberg J, Makker V. A Review of Immune Checkpoint Blockade Therapy in Endometrial Cancer. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-7.

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