INTRODUCTION

Human thrombin (brand names Artiss, Evarrest, Evicel, Evithrom, Tachosil, Tisseel, Vistaseal) is a platelet activating factor that is used for the treatment of minor bleeding.

This plasmid is designed for expressing Human thrombin in mammalian expression system such as HEK293 or Chinese hamster ovary (CHO) cell line.

PRODUCT INFORMATION

Item No.: PPBD-89
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options for promoter and selection marker, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Human thrombin
Brand Name(s): Artiss, Evarrest, Evicel, Evithrom, Tachosil, Tisseel, Vistaseal
Classification: Blood factors
Amino Acid Sequence: Identical to DB11571

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1]Mandell SP, Gibran NS. Fibrin sealants: surgical hemostat, sealant and adhesive. Expert Opin Biol Ther. 2014 Jun;14(6):821-30.

[2]Crawley JT, Zanardelli S, Chion CK, Lane DA. The central role of thrombin in hemostasis. J Thromb Haemost. 2007 Jul;5 Suppl 1:95-101.

Contact Us