INTRODUCTION

Insulin lispro (brand names Admelog, Humalog, Humalog Mix, Humalog kwikpen, Liprolog, Lyumjev) is a rapid-acting form of insulin analogue that is used for the treatment of hyperglycemia caused by Type 1 and Type 2 diabetes mellitus.

This plasmid is designed for expressing Insulin lispro in E.coli expression system or yeast expression system Saccharomyces cerevisiae.

PRODUCT INFORMATION

Item No.: PPBD-101
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Insulin lispro
Brand Name(s): Admelog, Humalog, Humalog Mix, Humalog kwikpen, Liprolog, Lyumjev
Classification: Insulins
Amino Acid Sequence: Identical to DB00030

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Herrmann BL, Kasser C, Keuthage W, Huptas M, Dette H, Klute A. Comparison of insulin aspart vs. regular human insulin with or without insulin detemir concerning adipozytokines and metabolic effects in patients with type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes. 2013 Apr;121(4):210-3.

[2] Lepore M, Pampanelli S, Fanelli C, Porcellati F, Bartocci L, Di Vincenzo A, Cordoni C, Costa E, Brunetti P, Bolli GB. Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro. Diabetes. 2000 Dec;49(12):2142-8.

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