INTRODUCTION

Pegaspargase (brand name Oncaspar) is a modified L-asparaginase (L-asparagine amidohydrolase) that is used in the treatment of acute lymphoblastic leukemia.

This plasmid is designed for expressing L-asparaginase (L-asparagine amidohydrolase) in E.coli expression system.

PRODUCT INFORMATION

Item No.: PPBD-141
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Pegaspargase
Brand Name(s): Oncaspar
Classification: Other protein based therapies
Amino Acid Sequence: Identical to DB00059

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Graham ML. Pegaspargase: a review of clinical studies. Adv Drug Deliv Rev. 2003 Sep 26;55(10):1293-302.

[1] Zeidan A, Wang ES, Wetzler M. Pegasparaginase: where do we stand? Expert Opin Biol Ther. 2009 Jan;9(1):111-9.

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