INTRODUCTION

Pegvisomant (brand name Somavert) is a growth hormone receptor antagonist that is used in the treatment of acromegaly.

This plasmid is designed for expressing Pegvisomant in E.coli expression system.

PRODUCT INFORMATION

Item No.: PPBD-147
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Pegvisomant
Brand Name(s): Somavert
Classification: Hormones
Amino Acid Sequence: Identical to DB00082

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Freda PU, Gordon MB, Kelepouris N, Jonsson P, Koltowska-Haggstrom M, van der Lely AJ. Long-term treatment with pegvisomant as monotherapy in patients with acromegaly: experience from ACROSTUDY. Endocr Pract. 2015 Mar;21(3):264-74.

[2] Schreiber I, Buchfelder M, Droste M, Forssmann K, Mann K, Saller B, Strasburger CJ; German Pegvisomant Investigators. Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: safety and efficacy evaluation from the German Pegvisomant Observational Study. Eur J Endocrinol. 2007 Jan;156(1):75-82.

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