INTRODUCTION

Protein S human (brand names Beriplex, Kcentra, Octaplex) is a vitamin K-dependent plasma glycoprotein that is used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy.

This plasmid is designed for expressing Protein S human in mammalian expression system such as HEK293 or Chinese hamster ovary (CHO) cell line.

PRODUCT INFORMATION

Item No.: PPBD-152
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Protein S human
Brand Name(s): Beriplex, Kcentra, Octaplex
Classification: Blood factors
Amino Acid Sequence: Identical to DB13149

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Rigby AC, Grant MA. Protein S: a conduit between anticoagulation and inflammation. Crit Care Med. 2004 May;32(5 Suppl):S336-41.

[2] Somajo S, Koshiar RL, Norström E, Dahlbäck B. Protein S and factor V in regulation of coagulation on platelet microparticles by activated protein C. Thromb Res. 2014 Jul;134(1):144-52.

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