INTRODUCTION

Rasburicase (brand names Elitek, Fasturtec) is a recombinant urate-oxidase enzyme that is used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.

This plasmid is designed for expressing Rasburicase in yeast expression system Saccharomyces cerevisiae.

PRODUCT INFORMATION

Item No.: PPBD-156
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Rasburicase
Brand Name(s): Elitek, Fasturtec
Classification: Recombinant Enzymes
Amino Acid Sequence: Identical to DB00049

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Collings I, Watier Y, Giffard M, Dagogo S, Kahn R, Bonneté F, Wright JP, Fitch AN, Margiolaki I. Polymorphism of microcrystalline urate oxidase from Aspergillus flavus. Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):539-48.

[2] Giraldez M, Puto K. A single, fixed dose of rasburicase (6 mg maximum) for treatment of tumor lysis syndrome in adults. Eur J Haematol. 2010 Aug;85(2):177-9.

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