INTRODUCTION

Tasonermin (brand name Beromun) is a recombinant soluble form of the tumor necrosis factor αlpha (TNF-a) that is use as an adjunt to surgery to remove soft tissue sarcomas of the limbs.

RGBiotech offers Tasonermin expression plasmid vector. This plasmid vector is designed for expressing Tasonermin in E.coli expression system.

PRODUCT INFORMATION

Item No.: PPBD-176
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Tasonermin
Brand Name(s): Beromun
Classification: Cytokine
Amino Acid Sequence: Identical to DB11626

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

[1] Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J. 1995 Jul;9(10):899-909.

[2] Wajant H, Pfizenmaier K, Scheurich P. Tumor necrosis factor signaling. Cell Death Differ. 2003 Jan;10(1):45-65.

[3] Zhang H, Park Y, Wu J, Chen Xp, Lee S, Yang J, Dellsperger KC, Zhang C. Role of TNF-alpha in vascular dysfunction. Clin Sci (Lond). 2009 Feb;116(3):219-30.

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