INTRODUCTION

Albutrepenonacog alfa (brand name Idelvion) is a recombinant fusion protein that links recombinant factor IX (rFIX) with recombinant human albumin (rAlbumin). It was approved for the treatment of haemophilia B.

This plasmid is designed for expressing Albutrepenonacog alfa in mammalian cells such as HEK293 or Chinese hamster ovary (CHO) cell.

PRODUCT INFORMATION

Item No.: PPBD-13
Shipping: Lyophilized plasmid, or liquid plasmid, or plasmids on filter paper
Storage: -20 °C or 4°C according to instruction
Plasmid Backbone: Expression plasmid, flexible options for promoter and antibiotic selection marker, custom available
Quality Control: Sequencing validation

DRUG INFORMATION

Generic Name: Albutrepenonacog alfa
Brand Names: Idelvion
Classification: Blood factors / Fusion proteins
Target: coagulation factor X (F10)
Action Type: Activator
Amino Acid Sequence: Identical to DB13884

PROTOCOL FOR PLASMID RECOVERY FROM FILTER PAPER

REFERENCE

Lyseng-Williamson KA. Coagulation Factor IX (Recombinant), Albumin Fusion Protein (Albutrepenonacog Alfa; Idelvion®): A Review of Its Use in Haemophilia B. Drugs. 2017 Jan;77(1):97-106.

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