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| Home -> Products & Services -> Cell Immortalization Plasmid Vectors -> HOXA10 Expression Plasmid Vector | ||
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HOXA10 Expression Plasmid Vector Item No.: PIM-010Shipping: 4 μg Storage: -20°C Homeobox A10 (HOXA10), also know as PL, HOX1, HOX1H, HOX1.8 in human, is a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. HOXA10 may function in fertility, embryo viability and regulation of hematopoietic lineage commitment. HOXA10 has been shown to interact with PTPN6. HOXA10 has the ability to immortalize myeloid progenitors in vitro. The interaction of HOXA9, HOXB8, and HOXA10 with Pbx1 and Meis1 is essential for immortalization and differentiation of myeloid progenitors. RGBiotech provides various types of plasmid vectors expressing human or mouse HOXB10 to assist your scientific research work in the field of primary cell immortalization. Please contact us for more product information as well as the price. Highlights -Our large collection of empty vector backbones can always allow you to find the fit-for-project plasmid vectors.-Sequencing validation to make sure zero mutation, -Competitive price APPlications -Production of viral particles by packaging viral-based plasmid vectors-Generation of immortalized cell line References [1] Negi V, Vishwakarma BA, Chu S, Oakley K, Han Y, Bhatia R, Du Y. Hoxa9 and Hoxa10 induce CML myeloid blast crisis development through activation of Myb expression. Oncotarget. 2017 Oct 24;8(58):98853-98864.[2] Sarno JL, Kliman HJ, Taylor HS. HOXA10, Pbx2, and Meis1 protein expression in the human endometrium: formation of multimeric complexes on HOXA10 target genes. J Clin Endocrinol Metab. 2005 Jan;90(1):522-8. |
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