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Cell Immortalization Plasmid Vectors

Cell immortalization is a technology that enables primary cells cultured in vitro escape the senescence phase of cell proliferation after a certain number of divisions to obtain the ability of infinite division. An immortal cell line is a convenient and reliable tool for studying scientific problems in cell-based biological research. To establish an immortal cell line, introduction of viral oncogenes/oncoproteins, myc genes, ectopic expression of telomerase, and the manipulation of genes that regulate the cell cycle, such as p53 and Rb, have been used.

RGBiotech offers a series of cell immortalized plasmid vector products that cover the most commonly used immortality genes driven by different promoters and contain flexible selection markers to facilitate your cell immortalization research.


Highlights
-Establish immortal cell line
-Non-viral and viral plasmid backbones

Item Name Item No. Description
[SV40 Small/Large T Antigen] Expression Plasmid Vector PIM-001 See More
[SV40 Large T Antigen] Expression Plasmid Vector PIM-002 See More
[HPV16 E6-E7] Expression Plasmid Vector PIM-003 See More
[HPV16 E6] Expression Plasmid Vector PIM-004 See More
[Human Ad5 E1A] Expression Plasmid Vector PIM-005 See More
TERT Expression Plasmid Vector PIM-006 See More
CDK4 Expression Plasmid Vector PIM-007 See More
HOXB8 Expression Plasmid Vector PIM-008 See More
HOXA9 Expression Plasmid Vector PIM-009 See More
HOXA10 Expression Plasmid Vector PIM-010 See More
MYC Expression Plasmid Vector PIM-011 See More
KRAS-Mutant Expression Plasmid Vector PIM-012 See More
Bmi1 Expression Plasmid Vector PIM-013 See More

 

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