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| Home -> Products & Services -> Cell Immortalization Plasmid Vectors -> [HPV16 E6] Expression Plasmid Vector | ||
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[HPV16 E6] Expression Plasmid Vector Item No.: PIM-004Shipping: 4 μg Storage: -20°C The E6 and E7 genes of human papillomavirus type 16 (HPV16) are efficient to immortalize a wide spectrum of cell types. HPV-16 E6 alone but not E7 alone is sufficient to immortalize human mammary epithelial cells. The transforming capability of the E6 gene is mediated by its interaction with p53 protein which leads to degradation of p53 protein through the ubiquitin-dependent protease system. RGBiotech provides various types of plasmid vectors expressing HPV16-E6 to assist your scientific research work in the field of primary cell immortalization. Please contact us for more product information as well as the price. Highights -Our large collection of empty vector backbones can always allow you to find the fit-for-project plasmid vectors.-Sequencing validation to make sure zero mutation, -Competitive price APPlications -Production of viral particles by packaging viral-based plasmid vectors-Generation of immortalized cell line References [1] Band V, De Caprio JA, Delmolino L, Kulesa V, Sager R. Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells. J Virol. 1991 Dec;65(12):6671-6. |
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