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| Home -> Products & Services -> Cell Immortalization Plasmid Vectors -> [SV40 Large T Antigen] Expression Plasmid Vector | ||
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[SV40 Large T Antigen] Expression Plasmid Vector Item No.: PIM-002Shipping: 4 μg Storage: -20°C Simian Virus 40 (SV40) Large T antigen has been widely used for genome integration to promote cell immortalization by preventing cell senescence and apoptosis. SV40 T Antigen binds to a variety of cellular factors which includes p53, pRB, DNA polymerase alpha-primase, and heat shock chaperone 70 (hsc70) to prolong the cell cycle and promote cell immortalization. So far, a large number of immortalized cell lines have been generated through SV40 Large T Antigen delivery. RGBiotech provides various types of plasmid vectors expressing SV40 Large T antigen to assist your scientific research work in the field of primary cell immortalization. Please contact us for more product information as well as the price. Highlights -Our large collection of empty vector backbones can always allow you to find the fit-for-project plasmid vectors. -Sequencing validation to make sure zero mutation, -Competitive priceAPPlications -Production of viral particles by packaging viral-based plasmid vectors -Generation of immortalized cell lineReferences [1] Chen Y, Hu S, Wang M, Zhao B, Yang N, Li J, Chen Q, Liu M, Zhou J, Bao G, Wu X. Characterization and Establishment of an Immortalized Rabbit Melanocyte Cell Line Using the SV40 Large T Antigen. Int J Mol Sci. 2019 Sep 30;20(19):4874. |
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