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| Home -> Products & Services -> Plasmid Platform -> SURETM TF Reporter Plasmids -> pSREBF1/RE-Reporter Plasmid | ||
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pSREBF1/RE-Reporter Plasmid Item No.: PSP019Shipping: Plasmids on filter paper, or liquid plasmids, or lyophilized plasmids Storage: As indicated in the product datasheet or product label; according to the delivered product form, for plasmids on filter paper, store at 4°C, for liquid or lyophilized plasmids, store at less than -20°C. INTRODUCTION Sterol regulatory element binding transcription factor 1 (SREBF1), also known as Sterol regulatory element-binding protein 1 (SREBP1), is a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that regulates the sterol biosynthesis pathway. Before entering the nucleus, SREBF1 is cleaved to its mature form that can recognize the sterol regulatory element-1 (SRE1) located in the promoter region of target genes. RGBiotech offers multiple types of pSREBF1/RE-Reporter plasmids that contains multiple tandem repeats of SREBF1 binding sites upstream of a reporter gene driven by a basal / minimal promoter. Our pSREBF1/RE-Reporter plasmids can be used in monitoring SREBF1 activities, screening of SREBF1 activitors / inhibitors / homologs, studying regulatory mechanism of SREBF1 gene expression, by simply detecting reporter gene expression after delivery of the plasmid into target cells. VECTOR INFORMATION -> Vector backbone options: non-viral mammalian expression plasmid, lentiviral expression plasmid, adenoviral expression plasmid, AAV expression plasmid-> Reporter gene options: GFP, RFP, Luciferase, SEAP, CAT -> Mammalian antibiotic selection options: none, puromycin, neomycin, hygromycin
Custom construction of pSREBF1/RE-Reporter Plasmid is also available at RGBiotech. Welcome to contact us at admin@rgbiotech.com for a quotation. |
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