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SURETM TF Reporter Plasmids

Transcription factors (TFs) are critical cellular components in regulation of gene expression. A typical TF contains two domains: 1) DNA-binding domain (DBD) which directs the TF to specific sequences of DNA adjacent to the genes that they regulate, 2) Trans-activating domain (TAD) which serves as a scaffold to recruit and assemble the transcription complex that initiates transcription. DNA sequences that recognized by TFs are called as transcription factor-binding sites or response elements, existing in either enhancer or promoter regions upstream of associated genes.

TFs are involved in many cellular pathways including cell development, intercellular signaling and cell cycle etc. Due to their important roles, many diseases are associated with abnormal TFs. Thus TFs are of great interest in elucidation of pathology mechanisms and drug development.

RGBiotech offers SURETM TF Reporter Plasmids that contain various TF binding sites controlled reporter gene expression cassette. Our SURETM TF Reporter Plasmids are effective tools for transcriptional regulation research.

- Screen novel TFs recognizing known DNA response elements
- Monitor activities of known TFs
- Screen activitors or inhibitors of TFs

Product List

Please find the plasmid of interest from the following list. For a quotation or inquiry on the product information, please contact us at admin@rgbiotech.com.

Item Name Item No. Response Element Description
pSP1/RE-Reporter Plasmid PSP001 Specificity protein 1 Response Element (Sp1/RE) See More
pYY1/RE-Reporter Plasmid PSP002 Yin Yang 1 Response Element (YY1/RE) See More
pMYC/RE-Reporter Plasmid PSP003 Myc Response Element (MYC/RE) See More
pNFY/RE-Reporter Plasmid PSP004 Nuclear transcription factor Y Response Element (NFY/RE) See More
pAP1/RE-Reporter Plasmid PSP005 Activator protein 1 Response Element (AP1/RE) See More
pMAZ/RE-Reporter Plasmid PSP006 Myc-associated zinc finger protein Response Element (MAZ/RE) See More
pCRE-Reporter Plasmid PSP007 cAMP response element (CRE) See More
pMYOD/RE-Reporter Plasmid PSP008 Myoblast determination protein 1 Response Element (MYOD/RE) See More
pELK1/RE-Reporter Plasmid PSP009 ETS transcription factor ELK1 Response Element (ELK1/RE) See More
pNRF1/RE-Reporter Plasmid PSP010 Nuclear respiratory factor 1 Response Element (NRF1/RE) See More
pGABP/RE-Reporter Plasmid PSP011 GA-binding protein Response Element (GABP/RE) See More
pSTAT1/RE-Reporter Plasmid PSP012 Signal transducer and activator of transcription 1 Response Element (STAT1/RE) See More
pAP4/RE-Reporter Plasmid PSP013 AP-4 Response Element (AP4/RE) See More
pSRY/RE-Reporter Plasmid PSP014 Sex-determining region Y Response Element (SRY/RE) See More
pTBP/RE-Reporter Plasmid PSP015 TATA-binding protein Response Element (TBP/RE) See More
pFOXO1/RE-Reporter Plasmid PSP016 Forkhead box O1 Response Element (FOXO1/RE) See More
pGTF2I/RE-Reporter Plasmid PSP017 General transcription factor II-I Response Element (GTF2I/RE) See More
pETV4/RE-Reporter Plasmid PSP018 ETS translocation variant 4 Response Element (ETV4/RE) See More
pSREBF1/RE-Reporter Plasmid PSP019 Sterol regulatory element binding transcription factor 1 Response Element (SREBF1/RE) See More
pNFκB/RE-Reporter Plasmid PSP020 Nuclear factor kappa-light-chain-enhancer of activated B cells Response Element (NF-κB/RE) See More
pATF6/RE-Reporter Plasmid PSP021 Activating transcription factor 6 Response Element (ATF6/RE) See More
pNFIL3/RE-Reporter Plasmid PSP022 Nuclear factor, interleukin 3 regulated Response Element (NFIL3/RE) See More
pSRF/RE-Reporter Plasmid PSP023 Serum response factor Response Element (SRF/RE) See More
pMEF2/RE-Reporter Plasmid PSP024 Myocyte enhancer factor 2A Response Element (MEF2/RE) See More
pPOU3F2/RE-Reporter Plasmid PSP025 POU class 3 homeobox 2 Response Element (POU3F2/RE) See More
pELF1/RE-Reporter Plasmid PSP026 E74 like ETS transcription factor 1 Response Element (ELF1/RE) See More
pBACH2/RE-Reporter Plasmid PSP027 BTB domain and CNC homolog 2 Response Element (BACH2/RE) See More
pMEIS1/RE-Reporter Plasmid PSP028 Meis homeobox 1 Response Element (MEIS1/RE) See More
pE2F/RE-Reporter Plasmid PSP029 E2F Response Element (E2F/RE) See More
pETS1/RE-Reporter Plasmid PSP030 ETS proto-oncogene 1, transcription factor Response Element (ETS1/RE) See More
pRFX1/RE-Reporter Plasmid PSP031 Regulatory Factor X1 Response Element (RFX1/RE) See More
pRORA/RE-Reporter Plasmid PSP032 RAR related orphan receptor A Response Element (RORA/RE) See More
pSPI1/RE-Reporter Plasmid PSP033 Spi-1 proto-oncogene Response Element (SPI1/RE) See More
pEGR1/RE-Reporter Plasmid PSP034 Early growth response 1 Response Element (EGR1/RE) See More
pEGR2/RE-Reporter Plasmid PSP035 RE1 silencing transcription factor Response Element (REST/RE) See More
pNFE2/RE-Reporter Plasmid PSP036 Nuclear factor, erythroid 2 Response Element (NFE2/RE) See More
pLEF1/RE-Reporter Plasmid PSP037 Lymphoid enhancer binding factor 1 Response Element (LEF1/RE) See More
pHNF3/RE-Reporter Plasmid PSP038 Hepatocyte nuclear factor 3 Response Element (HNF3/RE) See More
pZBTB18/RE-Reporter Plasmid PSP039 Zinc finger and BTB domain containing 18 Response Element (ZBTB18/RE) See More
pTEAD1/RE-Reporter Plasmid PSP040 TEA domain transcription factor 1 Response Element (TEAD1/RE) See More
pNKX2-5/RE-Reporter Plasmid PSP041 NK2 homeobox 5 Response Element (NKX2-5/RE) See More
pVSX2/RE-Reporter Plasmid PSP042 Visual system homeobox 2 Response Element (VSX2/RE) See More
pTCF4/RE-Reporter Plasmid PSP043 Transcription factor 4 Response Element (TCF4/RE) See More
pSTAT5/RE-Reporter Plasmid PSP044 Signal transducer and activator of transcription 5A Response Element (STAT5/RE) See More
pNKX6-2/RE-Reporter Plasmid PSP045 NK6 homeobox 2 Response Element (NKX6-2/RE) See More
pATF1/RE-Reporter Plasmid PSP046 Activating transcription factor 1 Response Element (ATF1/RE) See More
pPOU1F1/RE-Reporter Plasmid PSP047 POU class 1 homeobox 1 Response Element (POU1F1/RE) See More
pISRE-Reporter Plasmid PSP048 Interferon-stimulated Response Element (ISRE) See More
pSIE-Reporter Plasmid PSP049 Sis-inducible element (SIE) See More
pSBE-Reporter Plasmid PSP050 Smad binding element (SBE) See More
pARE-Reporter Plasmid PSP051 Antioxidant Response Element (ARE) See More
p53/RE-Reporter Plasmid PSP052 p53 Response Element (p53 RE) See More
pMRE-Reporter Plasmid PSP053 Metal Response Element (MRE) See More
pHSE-Reporter Plasmid PSP054 Heat shock Response Element (HSE) See More
pHRE-Reporter Plasmid PSP055 Hypoxia Response Element (HRE) See More
pXRE-Reporter Plasmid PSP056 Xenobiotic Response Element (XRE) See More
pNFAT/RE-Reporter Plasmid PSP057 Nuclear factor of activated T-cells Response Element (NFAT/RE) See More
pSRE-Reporter Plasmid PSP058 Serum Response Element (SRE) See More
pTCF-LEF/RE-Reporter Plasmid PSP059 Serum Response Element (SRE) See More
pVDR/RE-Reporter Plasmid PSP060 Vitamin D Receptor Response Element (VDRE) See More
pSTAT3/RE-Reporter Plasmid PSP061 Signal Transducer and Activator of Transcription 3 Response Element (STAT3/RE) See More
pSTAT4/RE-Reporter Plasmid PSP062 Signal Transducer and Activator of Transcription 4 Response Element (STAT4/RE) See More
pSTAT6/RE-Reporter Plasmid PSP063 Signal Transducer and Activator of Transcription 6 Response Element (STAT6/RE) See More
pSox2/RE-Reporter Plasmid PSP064 SRY (sex determining region Y)-box 2 Response Element (Sox2/RE) See More
pRAR/RE-Reporter Plasmid PSP065 Retinoic acid Response Element (RARE) See More
pRBP-JK/RE-Reporter Plasmid PSP066 RBP-JK Response Element (RBP-JK/RE) See More
pPR/RE-Reporter Plasmid PSP067 Progesterone Receptor Response Element (PRE) See More
pPPARγ/RE-Reporter Plasmid PSP068 PPARγ Response Element (PPRE) See More
pNanog/RE-Reporter Plasmid PSP069 Nanog homeobox Response Element (Nanog/RE) See More
pLXR/RE-Reporter Plasmid PSP070 Liver X Receptor Response Element (LXR/RE) See More
pKLF4/RE-Reporter Plasmid PSP071 Kruppel like factor 4 Response Element (KLF4/RE) See More
pIRF1/RE-Reporter Plasmid PSP072 Interferon Regulatory Factor 1 Response Element (IRF1/RE) See More
pHIF1/RE-Reporter Plasmid PSP073 Hypoxia-inducible Factor 1 Response Element (HIF1/RE) See More
pHNF1/RE-Reporter Plasmid PSP074 Hepatocyte Nuclear Factor 1 Response Element (HNF1/RE) See More
pHNF4/RE-Reporter Plasmid PSP075 Hepatocyte Nuclear Factor 4 Response Element (HNF4/RE) See More
pGRE-Reporter Plasmid PSP077 Glucocorticoid receptor Response Element (GRE) See More
pRXR/RE-Reporter Plasmid PSP078 Retinoid X receptor (RXR) Response Element (RXR/RE) See More
pGLI3/RE-Reporter Plasmid PSP079 GLI family zinc finger 3 Response Element (GLI3/RE) See More
pGAS/RE-Reporter Plasmid PSP080 Gamma-activated sequence Response Element (GAS/RE) See More
pAR/RE-Reporter Plasmid PSP081 Androgen Receptor Response Element (AR/RE) See More
pAhR/RE-Reporter Plasmid PSP082 Aryl hydrocarbon receptor Response Element (AhR/RE) See More
pPax6/RE-Reporter Plasmid PSP083 Paired box 6 Response Element (Pax6/RE) See More
pER/RE-Reporter Plasmid PSP084 Estrogen Receptor Response Element (ER/RE) See More
pOct4/RE-Reporter Plasmid PSP085 Oct4 Receptor Response Element (Oct4/RE) See More
pMR/RE-Reporter Plasmid PSP086 Mineralocorticoid receptor Response Element (MR/RE) See More
pFXR/RE-Reporter Plasmid PSP087 Farnesoid X receptor Response Element (FXR/RE) See More
pGAL4/RE-Reporter Plasmid PSP088 GAL4 Response Element (GAL4/RE) See More
pRb/RE-Reporter Plasmid PSP089 Retinoblastoma protein Response Element (Rb/RE) See More
pNRSF/RE-Reporter Plasmid PSP093 Neuron-Restrictive Silencer Factor Response Element (NRSF/RE) See More
pGATA/RE-Reporter Plasmid PSP094 Globin Transcription Factor Response Element (GATA/RE) See More
pc-Jun/RE-Reporter Plasmid PSP095 c-Jun Response Element (c-Jun/RE) See More
pBMP/RE-Reporter Plasmid PSP096 Bone Morphogenetic Protein Response Element (BMP/RE) See More
pAARE-Reporter Plasmid PSP097 Amino Acid Response Element (AARE) See More
pERSE-Reporter Plasmid PSP098 ER Stress Response Element (ERSE) See More
pAREB6/RE-Reporter Plasmid PSP099 AREB6/ZEB1 Response Element (AREB6/RE) See More
pGCNF/RE-Reporter Plasmid PSP100 GCNF (germ cell nuclear factor) / NR6A1 Response Element (GCNF/RE) See More
pC-REL/RE-Reporter Plasmid PSP101 C-REL Response Element (C-REL/RE) See More

 

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