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Home -> Products & Services -> Plasmid Platform -> SURETM TF Reporter Plasmids -> pNFκB/RE-Reporter Plasmid
 
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pNFκB/RE-Reporter Plasmid

Item No.: PSP020
Shipping: Plasmids on filter paper, or liquid plasmids, or lyophilized plasmids
Storage: As indicated in the product datasheet or product label; according to the delivered product form, for plasmids on filter paper, store at 4°C, for liquid or lyophilized plasmids, store at less than -20°C.

INTRODUCTION

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a transcription factor composed of proteins including RelA (p65), RelB, c-Rel, p50, and p52. NF-κB exhibits binding affinities to its specific DNA motifs with a consensus sequence 5'-GGGRNYYYCC-3' which can be found upstream of many genes from diverse biological pathways including immune response, inflammation, cell proliferation and cell death etc. RGBiotech offers multiple types of pNFκB/RE-Reporter plasmids that contains multiple tandem repeats of NFκB binding sites upstream of a reporter gene driven by a basal / minimal promoter. Our pNFκB/RE-Reporter plasmids can be used in monitoring NFκB activities, screening of NFκB activitors / inhibitors / homologs, studying regulatory mechanism of NFκB gene expression, by simply detecting reporter gene expression after delivery of the plasmid into target cells.

VECTOR INFORMATION

-> Vector backbone options: non-viral mammalian expression plasmid, lentiviral expression plasmid, adenoviral expression plasmid, AAV expression plasmid
-> Reporter gene options: GFP, RFP, Luciferase, SEAP, CAT
-> Mammalian antibiotic selection options: none, puromycin, neomycin, hygromycin

Custom construction of pNFκB/RE-Reporter Plasmid is also available at RGBiotech. Welcome to contact us at admin@rgbiotech.com for a quotation.

 

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